Trisomy 21 (Down syndrome) is a chromosomal abnormality characterized by the presence of an extra copy of the 21st chromosome.
Down syndrome is the most frequent genetic condition of childhood associated with mental retardation.
Maternal age is a major risk factor that increases the chance of conceiving a baby with Down syndrome. At maternal age 20
to 24, the probability of conceiving a child with Down Syndrome is 1 in 1,562; at age 35 to 39 the probability increases to
1 in 214; and above age 45 the probability increases to 1 in 19. However, though the probability of a child being born with
Down syndrome increases with maternal age, approximately 80% of children with Down syndrome are born to women under the age
of 35. There are currently no known environmental factors that are associated with developing Down syndrome.
Prevalence of Down Syndrome in Children Born to NJ Resident Mothers, Statewide Rates by Year, 2000-2007
Birth Certificate Database, Office of Vital Statistics and Registration, New Jersey Department of Health;
Early Identification and Monitoring Program, Special Child Health and Early Intervention Services, Division of Family Health
Services, New Jersey Department of Health;
Number of children born with Down syndrome per 10,000 live births to women residing in New Jersey in a specified time interval.
How We Calculated the Rates
Number of children born with Down syndrome among live births to women residing in New Jersey in a specified time interval.
Count of all live births to women residing in New Jersey in a specified time interval.
Page Content Updated On 10/09/12,
Published on 10/09/12
Special Child Health and Early Intervention Services, New Jersey Department of Health, PO Box 364, Trenton, NJ 08625-0364; Phone (609) 292-5676; Fax (609) 633-7820; Web: http://www.state.nj.us/health/fhs/index.shtml
Department of Health
P. O. Box 360, Trenton, NJ 08625-0360
Phone: (609) 292-7837
Toll-free in NJ: 1-800-367-6543 Our Locations
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